| Details | |
| Host / Isotype: | Rat / IgG1 |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | 7H8 |
| Species Reactivity: | Mouse (Ms) |
| Immunogen: | Murine C1q component of the C1 complex. |
| Ordering Information | ||||
| Pierce Complement C1q Antibody (7H8) |
| Storage: | 4° C |
| Form: | 1 ml of purified antibody (100 µg/ml) in PBS with 0.1% BSA and 0.02% Sodium Azide. |
| Applications | Dilution * |
| Functional Assay (FN) | Assay Dependent |
| Immunohistochemistry (Frozen) (IHC (F)) | Assay Dependent |
| ELISA (ELISA) | Assay Dependent |
| Immunofluorescence (IF) | Assay Dependent |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| MA1-40045 detects C1q from mouse samples. MA1-40045 has been successfully used in immunohistochemistry (frozen), ELISA, functional assays and immunofluorescence applications. The MA1-40045 immunogen is murine C1q component of the C1 complex. |
| General Information |
| This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. |