Part of Thermo Fisher Scientific

Collagen II Monoclonal Antibody (6B3)

Collagen II Antibody for IF, IHC (P)

Synonyms:
alpha-1 type II collagen, cartilage collagen, chondrocalcin, collagen II, alpha-1 polypeptide, collagen alpha-1(II) chain
Entrez Gene ID:
(Human) 1280
UniProt ID:
P02458
Details
Host / Isotype: Mouse / IgG1
Class: Monoclonal
Type: Antibody
Clone: 6B3
Species Reactivity: Human (Hu) Murine (Ms) Chicken (Ck) Amphibian (Am)
Immunogen: Purified type II collagen; obtained from the adult chicken sternum by limited pepsinization
Ordering Information
Pierce Collagen II Monoclonal Antibody (6B3)
Product Number Pkg. Size Price Purchase
MA5-13026 500 ul $282.00
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Storage: 4º C, DO NOT FREEZE!
Form: 500 ul of antibody purified from the ascites fluid by Protein G chromatography (200 ug/ml). Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.


Applications Dilution *
Immunofluorescence (IF) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 1-2 µg/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA5-13026 targets Collagen II in IF and IHC (P) applications and shows reactivity with Amphibian, Chicken, Human, and Murine samples.

The MA5-13026 immunogen is purified type II collagen; obtained from the adult chicken sternum by limited pepsinization.
General Information
This gene encodes the alpha-1 chain of type II collagen, a fibrillar collagen found in cartilage and the vitreous humor of the eye. Mutations in this gene are associated with achondrogenesis, chondrodysplasia, early onset familial osteoarthritis, SED congenita, Langer-Saldino achondrogenesis, Kniest dysplasia, Stickler syndrome type I, and spondyloepimetaphyseal dysplasia Strudwick type. In addition, defects in processing chondrocalcin, a calcium binding protein that is the C-propeptide of this collagen molecule, are also associated with chondrodysplasia. There are two transcripts identified for this gene.
Product Images
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  • IHC using MA5-13026
    Immunohistochemistry with anti-Collagen II Monoclonal Antibody [6B3] (MA5-13026)

    Immunohistochemistry with anti-Collagen II Monoclonal Antibody [6B3] (MA5-13026)

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    Formalin-fixed, paraffin-embedded human fetus stained with Collagen II antibody using peroxidase-conjugate and AEC chromogen. Note staining of matrix in the cartilaginous plates.
     
 
 
(This product is for In Vitro experimental use only. Not for resale without express authorization.)