CD79a Antibody, Biotin conjugate (HM47/A9)

CD79a Monoclonal Antibody for IF, Western blot

>> See 11 other antibodies for CD79A (B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein)

Synonyms:

B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein

Entrez Gene ID:

(Hu) 973, (Ms) 12518, (Rt) 681236

UniProt ID:

(Hu) P11912, (Ms) P11911

Details

Host / Isotype:	Mouse / IgG1, kappa
Class:	Monoclonal
Type:	Antibody
Clone:	HM47/A9
Label:	Biotin
Species Reactivity:	Guinea Pig (Gp) Human (Hu) Mouse (Ms) Rat (Rt) Rabbit (Rb) Non-human primate (Nhp) Bovine (Bv) Porcine (Po) Equine (Eq)
Immunogen:	A synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein

Ordering Information
Pierce CD79a Antibody, Biotin conjugate (HM47/A9)

Product #

MA5-13209

Size

500 ul

Price

$346.00

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Storage:	4° C, do not freeze
Form:	500 ul of antibody purified from the ascites fluid by Protein G chromatography (200 ug/ml). Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide.

Applications	Dilution *

Immunofluorescence (IF)	Assay Dependent
Western Blot (WB)	0.5-1.0 µg/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Product Specific Information

MA5-13209 targets CD79a in IF and WB applications and shows reactivity with Bovine, Equine, Guinea Pig, Human, Murine, Non-human primate, Porcine, Rabbit, and Rat samples.

The MA5-13209 immunogen is a synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein.

General Information

A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.

Product Images

CD79a Antibody (MA5-13209) in WB

Western Blot with anti-CD79a Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

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Western blot of CD79a using CD79a Monoclonal Antibody (MA5-13209) on Raji Cells.

PubMed References:

IHC (3)

Immunohistochemistry
	Species / Dilution	Summary
	Ms / Not Cited	MA5-13209 was used in immunohistochemistry to investigate the involvement NFATc3 in T-cell lymphomagenesis by murine leukemia virus Blood. 2005 Nov 15;106(10):3546-52. "A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus." Author(s): Glud SZ, Sørensen AB, Andrulis M, Wang B, Kondo E, Jessen R, Krenacs L, Stelkovics E, Wabl M, Serfling E, Palmetshofer A, Pedersen FS Number of Citations: 12 (See PubMed article )
	Rt / 0	MA5-13209 was used in immunohistochemistry to study the mechanism of increased polyamine production and apoptosis during Pneumocystis pneumonia J Biol Chem. 2009 Mar 20;284(12):8174-84. "Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages." Author(s): Liao CP, Lasbury ME, Wang SH, Zhang C, Durant PJ, Murakami Y, Matsufuji S, Lee CH Number of Citations: 6 (See PubMed article )
	Rt / 0	MA5-13209 was used in immunohistochemistry to study the susceptibility to spontaneous and carcinogen-induced tumorigenesis in p53-deficient rats Carcinogenesis. 2012 Oct;33(10):2001-5. "Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis." Author(s): Yan HX, Wu HP, Ashton C, Tong C, Ying QL Number of Citations: 1 (See PubMed article )

(This product is for In Vitro experimental use only. Not for resale without express authorization.)