CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9)

CD79a / Ig alpha Monoclonal Antibody for Western blot, IF, IHC (P)

>> See 12 other antibodies for CD79A (B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein)
Synonyms:
B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein
Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: HM47/A9
Label: Biotin
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Bovine (Bv), Chicken (Ck), Equine (Eq), Guinea Pig (GP), Non-human primate (Nhp), Porcine (Po), Rabbit (Rb)
Published Species Reactivity: Mouse (Ms), Rat (Rt)
Immunogen: A synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein
Ordering Information
Pierce CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9)
Product #
MA5-13209
Size
500 ul
Price
$350.00
Purchase
Add CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9) to your cart.
Tested Applications Dilution *
Western Blot (WB) 0.5-1.0 µg/ml
Immunofluorescence (IF) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 0.5-1 ug/ml
Published Applications Dilution
Immunohistochemistry (IHC) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.2mg/ml
Purification: Protein G
Storage Buffer: PBS, pH 7.4, with 0.2% BSA
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
MA5-13209 targets CD79a in IF, IHC (P) and WB applications and shows reactivity with Bovine, Equine, Guinea Pig, Human, mouse, Non-human primate, Porcine, Rabbit, chicken and Rat samples.

The MA5-13209 immunogen is a synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein.
General Information
A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.
Product Images
  • CD79a / Ig alpha Antibody (MA5-13209) in WB
    MA5-13209_WesternBlot.jpg

    Western Blot with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13209_WesternBlot.jpg)

    Western Blot with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Western blot of CD79a using CD79a Monoclonal Antibody (MA5-13209) on Raji Cells.
  • CD79a / Ig alpha Antibody (MA5-13209) in IHC (P)
    MA5-13212_Immunohistochemistry_01162014.jpg

    Immunohistochemistry (Paraffin) with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13212_Immunohistochemistry_01162014.jpg)

    Immunohistochemistry (Paraffin) with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Formalin-fixed, paraffin-embedded human tonsil stained with CD79-alpha antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of B-lymphocytes.
  • CD79a / Ig alpha Antibody (MA5-13209) in IHC (P)
    MA5-13212_Immunohistochemistry_2_01162014.jpg

    Immunohistochemistry (Paraffin) with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13212_Immunohistochemistry_2_01162014.jpg)

    Immunohistochemistry (Paraffin) with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Formalin-fixed, paraffin-embedded rat spleen stained with CD79a antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of lymphocytes.
Publications:
Immunohistochemistry
  Species / Dilution Summary
  Ms / Not Cited
MA5-13209 was used in immunohistochemistry to investigate the involvement NFATc3 in T-cell lymphomagenesis by murine leukemia virus

Blood. 2005 Nov 15;106(10):3546-52.
"A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus."
Author(s): Glud SZ, Sørensen AB, Andrulis M, Wang B, Kondo E, Jessen R, Krenacs L, Stelkovics E, Wabl M, Serfling E, Palmetshofer A, Pedersen FS
Number of Citations: 12
(See PubMed article )
  Rt / 0
MA5-13209 was used in immunohistochemistry to study the mechanism of increased polyamine production and apoptosis during Pneumocystis pneumonia

J Biol Chem. 2009 Mar 20;284(12):8174-84.
"Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages."
Author(s): Liao CP, Lasbury ME, Wang SH, Zhang C, Durant PJ, Murakami Y, Matsufuji S, Lee CH
Number of Citations: 6
(See PubMed article )
  Rt / 0
MA5-13209 was used in immunohistochemistry to study the susceptibility to spontaneous and carcinogen-induced tumorigenesis in p53-deficient rats

Carcinogenesis. 2012 Oct;33(10):2001-5.
"Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis."
Author(s): Yan HX, Wu HP, Ashton C, Tong C, Ying QL
Number of Citations: 1
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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