CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9)

CD79a / Ig alpha Monoclonal Antibody for Western blot, IF, IHC (P)

>> See 12 other antibodies for CD79A (B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein)
Synonyms:
B-cell antigen receptor complex-associated protein alpha chain, CD79a antigen (immunoglobulin-associated alpha), MB-1 membrane glycoprotein, ig-alpha, membrane-bound immunoglobulin-associated protein, surface IgM-associated protein
Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: HM47/A9
Label: Biotin
Tested Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt), Bovine (Bv), Chicken (Ck), Equine (Eq), Guinea Pig (GP), Non-human primate (Nhp), Porcine (Po), Rabbit (Rb)
Published Species Reactivity: Human (Hu), Mouse (Ms), Rat (Rt)
Immunogen: A synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein
Ordering Information
Pierce CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9)
Product #
MA5-13209
Size
500 ul
Price
$350.00
Purchase
Add CD79a / Ig alpha Antibody, Biotin conjugate (HM47/A9) to your cart.
Tested Applications Dilution *
Western Blot (WB) 0.5-1.0 µg/ml
Immunofluorescence (IF) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 0.5-1 ug/ml
Published Applications Dilution
Immunohistochemistry (IHC) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.2mg/ml
Purification: Protein G
Storage Buffer: PBS, pH 7.4, with 0.2% BSA
Preservative: 0.09% sodium azide
Storage Conditions: 4° C
Product Specific Information
MA5-13209 targets CD79a in IF, IHC (P) and WB applications and shows reactivity with Bovine, Equine, Guinea Pig, Human, mouse, Non-human primate, Porcine, Rabbit, chicken and Rat samples.

The MA5-13209 immunogen is a synthetic peptide consisting of GTYQDVGSLNIADVQ of human CD79a protein.
General Information
A disulphide-linked heterodimer, consisting of mb-1 (or CD79a) and B29 (or CD79b) polypeptides, is non-covalently associated with membrane-bound immunoglobulins on B cells to constitute the B cell Ag receptor. CD79a first appears at pre B cell stage and persists until the plasma cell stage where it is found as an intracellular component. CD79a is found in the majority of acute leukemias of precursor B cell type, in B cell lines, B cell lymphomas, and in some myelomas. It is not present in myeloid or T cell lines.
Product Images
  • CD79a / Ig alpha Antibody (MA5-13209) in WB
    MA5-13209_WesternBlot.jpg

    Western Blot with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13209_WesternBlot.jpg)

    Western Blot with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Western blot of CD79a using CD79a Monoclonal Antibody (MA5-13209) on Raji Cells.
  • CD79a / Ig alpha Antibody (MA5-13209) in IHC (P)
    MA5-13212_Immunohistochemistry_01162014.jpg

    Immunohistochemistry (Paraffin) with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13212_Immunohistochemistry_01162014.jpg)

    Immunohistochemistry (Paraffin) with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Formalin-fixed, paraffin-embedded human tonsil stained with CD79-alpha antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of B-lymphocytes.
  • CD79a / Ig alpha Antibody (MA5-13209) in IHC (P)
    MA5-13212_Immunohistochemistry_2_01162014.jpg

    Immunohistochemistry (Paraffin) with anti-CD79a  /  Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209) (MA5-13212_Immunohistochemistry_2_01162014.jpg)

    Immunohistochemistry (Paraffin) with anti-CD79a / Ig alpha Monoclonal Antibody [HM47/A9], Biotin conjugate (MA5-13209)

    Formalin-fixed, paraffin-embedded rat spleen stained with CD79a antibody using peroxidase-conjugate and AEC chromogen. Note cell membrane staining of lymphocytes.
Publications:
Immunohistochemistry
  Species / Dilution Summary
  Hu / Not Cited
MA5-13209 was used in immunohistochemistry to evaluate 43 cases of blastic plasmacytoid dendritic cell neoplasm with leukemic presentation

Haematologica. 2013 Feb;98(2):239-46.
"Blastic plasmacytoid dendritic cell neoplasm with leukemic presentation: an Italian multicenter study."
Author(s): Pagano L, Valentini CG, Pulsoni A, Fisogni S, Carluccio P, Mannelli F, Lunghi M, Pica G, Onida F, Cattaneo C, Piccaluga PP, Di Bona E, Todisco E, Musto P, Spadea A, D'Arco A, Pileri S, Leone G, Amadori S, Facchetti F
Number of Citations: 6
(See PubMed article )
  Ms / Not Cited
MA5-13209 was used in immunohistochemistry to investigate the involvement NFATc3 in T-cell lymphomagenesis by murine leukemia virus

Blood. 2005 Nov 15;106(10):3546-52.
"A tumor-suppressor function for NFATc3 in T-cell lymphomagenesis by murine leukemia virus."
Author(s): Glud SZ, Sørensen AB, Andrulis M, Wang B, Kondo E, Jessen R, Krenacs L, Stelkovics E, Wabl M, Serfling E, Palmetshofer A, Pedersen FS
Number of Citations: 12
(See PubMed article )
  Rt / 0
MA5-13209 was used in immunohistochemistry to study the mechanism of increased polyamine production and apoptosis during Pneumocystis pneumonia

J Biol Chem. 2009 Mar 20;284(12):8174-84.
"Pneumocystis mediates overexpression of antizyme inhibitor resulting in increased polyamine levels and apoptosis in alveolar macrophages."
Author(s): Liao CP, Lasbury ME, Wang SH, Zhang C, Durant PJ, Murakami Y, Matsufuji S, Lee CH
Number of Citations: 6
(See PubMed article )
  Rt / 0
MA5-13209 was used in immunohistochemistry to study the susceptibility to spontaneous and carcinogen-induced tumorigenesis in p53-deficient rats

Carcinogenesis. 2012 Oct;33(10):2001-5.
"Rats deficient for p53 are susceptible to spontaneous and carcinogen-induced tumorigenesis."
Author(s): Yan HX, Wu HP, Ashton C, Tong C, Ying QL
Number of Citations: 1
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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