CD49f / Integrin alpha 6 Antibody (CLB-701)

CD49f / Integrin alpha 6 Monoclonal Antibody for IF, IHC, FACS

>> See 13 other antibodies for ITGA6 (CD49f, DKFZp686J01244, FLJ18737, ITGA6B, VLA-6)
Synonyms:
CD49f, DKFZp686J01244, FLJ18737, ITGA6B, VLA-6
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rat / IgG2a
Class: Monoclonal
Type: Antibody
Clone: CLB-701
Tested Species Reactivity: Human (Hu)
Published Species Reactivity: Human (Hu)
Immunogen: CD49f.
Ordering Information
Pierce CD49f / Integrin alpha 6 Antibody (CLB-701)
Product #
MA1-35230
Size
1 ml
Price
$599.00
Purchase
Add CD49f / Integrin alpha 6 Antibody (CLB-701) to your cart.
Tested Applications Dilution *
Immunofluorescence (IF) Assay dependent.
Immunohistochemistry (IHC) Assay dependent.
Flow Cytometry (FACS) Assay dependent.
Published Applications Dilution
Immunohistochemistry (IHC) See publications below
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.2mg/ml
Purification: purified
Storage Buffer: TBS, pH 8.0, with 10mg BSA
Preservative: 0.001% thimerosal
Storage Conditions: 4° C
Product Specific Information
MA1-35230 detects CD49f in human samples.

MA1-35230 has been successfully used in immunohistochemistry, flow cytometry and immunofluorescence applications.

The MA1-35230 immunogen is from the CD49f antigen.
General Information
The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as TSP180, or with beta 1 in the integrin VLA-6. Integrins are known to participate in cell adhesion as well as cell-surface mediated signalling. Two transcript variants encoding different isoforms have been found for this gene.
Publications:
Immunohistochemistry
  Species / Dilution Summary
  Hu / 1:50
MA1-35230 was used in immunohistochemistry to identity the CD44posCD49fhiCD133/2hi cells as tumorigenic in murine xenograft models

Cancer Res. 2010 Jun 1;70(11):4624-33.
"CD44posCD49fhiCD133/2hi defines xenograft-initiating cells in estrogen receptor-negative breast cancer."
Author(s): Meyer MJ, Fleming JM, Lin AF, Hussnain SA, Ginsburg E, Vonderhaar BK
Number of Citations: 6
(See PubMed article )
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific