CD331 / FGFR1 Antibody

CD331 / FGFR1 Polyclonal Antibody for Western blot, IHC (P)

>> See 21 other antibodies for FGFR1 (BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, KAL2, N-SAM, OGD, bFGF-R-1, FGFR1/PLAG1 fusion, FMS-like tyrosine kinase 2, basic fibroblast growth factor receptor 1, fms-related tyrosine kinase 2, heparin-binding growth factor receptor, hydroxyaryl-protein kinase, proto-oncogene c-Fgr)
Synonyms:
BFGFR, CD331, CEK, FGFBR, FGFR-1, FLG, FLT-2, FLT2, HBGFR, KAL2, N-SAM, OGD, bFGF-R-1, FGFR1/PLAG1 fusion, FMS-like tyrosine kinase 2, basic fibroblast growth factor receptor 1, fms-related tyrosine kinase 2, heparin-binding growth factor receptor, hydroxyaryl-protein kinase, proto-oncogene c-Fgr
Entrez Gene ID:
UniProt ID:
Details
Host / Isotype: Rabbit / IgG
Class: Polyclonal
Type: Antibody
Tested Species Reactivity: Human (Hu), Mouse (Ms)
Immunogen: Recombinant fragment contain a sequence corresponding to a region within amino acids 1 and 820 of FGFR1
Ordering Information
Pierce CD331 / FGFR1 Antibody
Product #
PA5-28564
Size
100 ul
Price
$316.00
Purchase
Add CD331 / FGFR1 Antibody to your cart.
Tested Applications Dilution *
Western Blot (WB) 1:500-1:3000
Immunohistochemistry (Paraffin) (IHC (P)) 1:100-1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Concentration: 0.39mg/ml
Purification: Antigen affinity chromatography
Storage Buffer: 0.1M tris, pH 7, with 10% glycerol, 0.1M glycine
Preservative: 0.01% thimerosal
Storage Conditions: -20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-28564 targets FGFR1 in IHC (P) and WB applications and shows reactivity with Human and mouse samples.

The PA5-28564 immunogen is recombinant protein fragment corresponding to a region within amino acids 1 and 820 of Human FGFR1.
General Information
The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction. Mutations in this gene have been associated with Pfeiffer syndrome, Jackson-Weiss syndrome, Antley-Bixler syndrome, osteoglophonic dysplasia, and autosomal dominant Kallmann syndrome 2. Chromosomal aberrations involving this gene are associated with stem cell myeloproliferative disorder and stem cell leukemia lymphoma syndrome. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.
Product Images
  • CD331 / FGFR1 Antibody (PA5-28564) in WB
    FGFR1_PA5-28564_Antibody_WesternBlot.jpg

    Western Blot with anti-CD331  /  FGFR1  Polyclonal Antibody (PA5-28564) (FGFR1_PA5-28564_Antibody_WesternBlot.jpg)

    Western Blot with anti-CD331 / FGFR1 Polyclonal Antibody (PA5-28564)

    Western Blot analysis of FGFR1 using anti-FGFR1 Polyclonal Antibody (PA5-28564), in Mouse Brain (50 ug of cell lysate) and at a dilution of 1:1000.
  • CD331 / FGFR1 Antibody (PA5-28564) in WB
    FGFR1_PA5-28564_Antibody_WesternBlot_2.jpg

    Western Blot with anti-CD331  /  FGFR1  Polyclonal Antibody (PA5-28564) (FGFR1_PA5-28564_Antibody_WesternBlot_2.jpg)

    Western Blot with anti-CD331 / FGFR1 Polyclonal Antibody (PA5-28564)

    Western Blot analysis using anti-FGFR1 Polyclonal Antibody on the following cells: (30 ug of whole cell lysate) A: Hela B: Molt-4 cell lysate. Primary antibody (PA5-28564) diluted at 1:1000
  • CD331 / FGFR1 Antibody (PA5-28564) in IHC
    FGFR1_PA5-28564_Antibody_Immunohistochemistry.jpg

    Immunohistochemistry with anti-CD331  /  FGFR1  Polyclonal Antibody (PA5-28564) (FGFR1_PA5-28564_Antibody_Immunohistochemistry.jpg)

    Immunohistochemistry with anti-CD331 / FGFR1 Polyclonal Antibody (PA5-28564)

    Immunohistochemical analysis of paraffin-embedded TOV-112D xenograft using FGFR1 (PA5-28564) antibody at 1:100 dilution.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
Part of Thermo Fisher Scientific