Part of Thermo Fisher Scientific

CCR6 Monoclonal Antibody (53103.111)

CCR6 Antibody for FACS, IHC (F)

Synonyms:
BN-1, CD196, CKR-L3, CKR6, CKRL3, CMKBR6, DCR2, DRY-6, GPR-CY4, GPR29, GPRCY4, STRL22
Entrez Gene ID:
(Human) 1235
UniProt ID:
P51684
Details
Host / Isotype: Mouse / IgG2b
Class: Monoclonal
Type: Antibody
Clone: 53103.111
Species Reactivity: Human (Hu)
Immunogen: Human CCR6 transfected NSO mouse myeloma cells.
Ordering Information
Pierce CCR6 Monoclonal Antibody (53103.111)
Product Number Pkg. Size Price Purchase
MA1-20156 100 µg $327.00
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Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: 100 µg of Protein G purified antibody (0.5 mg/ml) in PBS.


Applications Dilution *
Flow Cytometry (FACS) 5µg/10E5cells
Immunohistochemistry (Frozen) (IHC (F)) Assay dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA1-20156 detects CCR6 in human samples.

MA1-20156 has been successfully used in FACS and immunohistochemistry (frozen) procedures.

The MA1-20156 immunogen is human CCR6 transfected NSO mouse myeloma cells.
General Information
Chemokines have been sub-divided into families on the basis of the relative position of their cysteine residues. The a- and b- families, with four cysteine residues, are the largest and best characterized. CCR-6 (previously referred to as the GPR-CY4, CKRL3, or STRL22 orphan receptor) binds MIP-3". It is a CC chemokine receptor that is highly expressed in human dendritic cells derived from CD34+ cord blood precursors.2-4 In addition to dendritic cells, CCR-6 mRNA has also been detected in lymphocytes (CD4 and CD8 T cells and B cells), but not in natural killer cells, monocytes and granulocytes.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)