* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
0.1% sodium azide
Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Product Specific Information
PA1-46313 reacts with Band 4.1-like protein 3 in human, mouse, rat and xenopus samples.
PA1-46313 has been successfully used in Western Blot applications.
The PA1-46313 immunogen is a synthetic peptide made to an internal region of human EPB41L3 (within residues 400-500).
Protein 4.1B is a member of a family of similar proteins whose expression is frequently lost in a variety of human tumors, including meningiomas, non-small-cell lung cancers, and breast carcinomas and is frequently down-regulated in human clinical prostate cancer. Studies have shown that Protein 4.1B normally triggers death in metastatic cells, thereby preventing cancer from spreading. A clinical test for Protein 4.1B activity could be useful in assessing the metastatic potential of prostate cancers.
Band 4.1-like protein 3 Antibody (PA1-46313) in WB PA1-46313_Westernblot.jpg
Western Blot with anti-Band 4.1-like protein 3 Polyclonal Antibody (PA1-46313)