Part of Thermo Fisher Scientific

BMP-1 Polyclonal Antibody

BMP-1 Antibody for Western blot

Synonyms:
FLJ44432, PCOLC, PCP, TLD, pCP-2
Entrez Gene ID:
(Human) 649
UniProt ID:
P13497
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide of Human BMP-1.
Ordering Information
Pierce BMP-1 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
GB-10001 250 µl $293.00
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This product is not available outside of the U.S.

Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 250 μl of antibody provided as lyophillized crude antiserum


Applications Dilution *
Western Blot (WB) 1:50,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
GB-10001 detects BMP-1 in human samples.

GB-10001 has been successfully used in ELISA procedures.

The GB-10001 immunogen is a synthetic peptide located on the putative metalloproteasedomain corresponding to residues 121-321) of human BMP-1.
General Information
The BMP-1 (Bone Morphogenic Protein-1) locus encodes a protein that is capable of inducing formation of cartilage in vivo. Although other bone morphogenetic proteins are members ofthe TGF-beta superfamily, BMP-1 encodes a protein that is not closely related to other known growth factors. BMP-1 protein and procollagen C proteinase (PCP), a secreted metalloprotease requiring calcium and needed for cartilage and bone formation, are identical. PCP or BMP1 protein cleaves the C-terminal propeptides of procollagen I, II, and III and its activity is increased by the procollagen C-endopeptidase enhancer protein. The BMP1 gene is expressed as alternatively spliced variants that share an N-terminal protease domain but differ in their C-terminal region.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)