* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
0.1M tris, pH 7,
10% glycerol, 0.1M glycine
-20° C, Avoid Freeze/Thaw Cycles
Product Specific Information
PA5-27384 targets BLM in IF, IHC (P), and WB applications and shows reactivity with Human samples.
The PA5-27384 immunogen is recombinant fragment corresponding to a region within amino acids 1235 and 1417 of Human BLM.
The Bloom syndrome gene product is related to the RecQ subset of DExH box-containing DNA helicases and has both DNA-stimulated ATPase and ATP-dependent DNA helicase activities. Mutations causing Bloom syndrome delete or alter helicase motifs and may disable the 3'-5' helicase activity. The normal protein may act to suppress inappropriate recombination.
BLM Antibody (PA5-27384) in WB BLM_PA5-27384_Antibody_WesternBlot.jpg
Western Blot with anti-BLM Polyclonal Antibody (PA5-27384)