* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
tissue culture supernatant
0.09% sodium azide
Product Specific Information
MA5-11617 targets Amyloid Beta in IHC (P) applications and shows reactivity with Human samples.
The MA5-11617 immunogen is a synthetic peptide consisting of residues 8-17 (SGYEVHHQKL) of the amyloid beta-protein/amyloid A4 which is the same as aa 660-669 of human amyloid A4 / amyloid Beta protein precursor.
Amyloid beta-protein/amyloid A4 or amyloid beta-peptide is derived from the amyloid beta-precursor protein. Beta amyloid is an extracellular filamentous protein deposit found in the brain. It is the major protein component of amyloid cores, neuritic plaques and is also found as a deposit in neurofibrillary tangles. In man, Alzheimer's disease is the most common cause of senile dementia and is characterized by abnormal filamentous protein deposits in the brain. Beta amyloid deposits are also detected in Lewy body dementia, Down's syndrome, amyloidosis (Dutch type) and in the Guam Parkinson-Dementia complex.
Amyloid Beta Antibody (MA5-11617) in IHC MA5-11617_Immunohistochemistry.jpg
Immunohistochemistry with anti-Amyloid Beta Monoclonal Antibody [BAM01 (6F/3D)] (MA5-11617)