Part of Thermo Fisher Scientific

Actin Skeletal Muscle Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1))

Actin Skeletal Muscle Antibody for IF, IHC (P)

Synonyms:
actin, alpha skeletal muscle, alpha skeletal muscle actin, alpha-actin-1
Entrez Gene ID:
(Human) 58
UniProt ID:
P68133
Details
Host / Isotype: Mouse / IgM, kappa
Class: Monoclonal
Type: Antibody
Clone: 5C5.F8.C7 (alpha-Sr-1)
Species Reactivity: Human (Hu) Rat (Rt) Rabbit (Rb) Bovine (Bv) Ovine (Ov) Amphibian (Am) Guinea Pig (Gp)
Immunogen: N-terminal decapeptide
Ordering Information
Pierce Actin Skeletal Muscle Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1))
Product Number Pkg. Size Price Purchase
MA5-12542 500 ul $236.00
Add Actin Skeletal Muscle Monoclonal Antibody (5C5.F8.C7 (alpha-Sr-1)) to your cart.


Storage: 4ยบ C, DO NOT FREEZE!
Form: 500 ul of antibody purified from ascites fluid by ammonium sulfate precipitation (200 ug/ml) and prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% azide.


Applications Dilution *
Immunofluorescence (IF) Assay Dependent
Immunohistochemistry (Paraffin) (IHC (P)) 1:200
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA5-12542 targets Actin Skeletal Muscle in IF and IHC (P) applications and shows reactivity with Amphibian, Bovine, Guinea Pig, Human, Ovine, Rabbit, and Rat samples.

The MA5-12542 immunogen is n-terminal decapeptide.
General Information
The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects.
Product Images
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  • IHC using MA5-12542
    Immunohistochemistry with anti-Actin Skeletal Muscle Monoclonal Antibody [5C5.F8.C7 (alpha-Sr-1)] (MA5-12542)

    Immunohistochemistry with anti-Actin Skeletal Muscle Monoclonal Antibody [5C5.F8.C7 (alpha-Sr-1)] (MA5-12542)

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    Formalin-fixed, paraffin-embedded human skeletal muscle stained with Skeletal Muscle Actin antibody using peroxidase-conjugate and DAB chromogen. Note cytoplasmic staining of skeletal muscle cells.
     
 
 
(This product is for In Vitro experimental use only. Not for resale without express authorization.)