* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Antigen affinity chromatography
PBS, pH 7.4,
0.09% sodium azide
4° C, do not freeze
Product Specific Information
PA1-21004 detects APC in Human, Mouse and Rat samples.
PA1-21004 has been successfully used in Immunohistochemistry (Paraffin), Immunoprecipitation and Western Blot procedures.
PA1-21004 immunogen corresponds to Synthetic peptide corresponding to the C-terminal region of the human protein. .
This gene encodes a tumor suppressor protein that includes among its many intracellular functions one of nuclear export. Defects in this gene cause familial adenomatous polyposis (FAP), an autosomal dominant pre-malignant disease that usually progresses to malignancy. Disease-associated mutations tend to be clustered in a small region designated the mutation cluster region (MCR) and result in a truncated protein product.
APC Antibody (PA1-21004) in IHC PA1-21004_IHC_2.jpg
Immunohistochemistry with anti-APC Polyclonal Antibody (PA1-21004)