Part of Thermo Fisher Scientific

APC-AAT complexes, neoepitope Monoclonal Antibody (7)

APC-AAT complexes, neoepitope Antibody for ELISA

Details
Host / Isotype: Mouse / IgG1, kappa
Class: Monoclonal
Type: Antibody
Clone: 7
Species Reactivity: Human (Hu)
Immunogen: Recombinant form of human activated protein C.
Ordering Information
Pierce APC-AAT complexes, neoepitope Monoclonal Antibody (7)
Product Number Pkg. Size Price Purchase
ABS 001-07-02 200 µg $386.00
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Storage: 4º C, store in dark
Form: 200 µg of Protein A/G purified antibody (1 mg/ml) in 0.01 M phosphate buffer, with 0.5 M NaCl and 15 mM sodium azide; pH 7.4.


Applications Dilution *
ELISA (ELISA) 1:500
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
ABS 001-07-02 has specificity for a conformation-dependant neoepitope that is expressed in activated protein C upon complex-formation with alpha1-antitrypsin. No reaction is seen to non-complexed alpha1-antitrypsin and only very little cross reaction to protein C zymogen. Note that specificity is calcium dependent.
 
ABS 001-07-02 has been successfully used in ELISA procedures. ABS 001-07-02 reacts strongly with APC-AAT complexes in ELISA. It can be used in sandwich ELISA in combination with a polyclonal anti-protein C antiserum. Note, that the conformational neoepitope expressed in the complex can also be expressed in APC coated directly onto a high-binding microtiter plate.

The ABS 001-07-02 immunogen is the recombinant form of human activated protein C.

The epitope specificity of ABS 001-07-02 is not determined.
General Information
(This product is for In Vitro experimental use only. Not for resale without express authorization.)