AMPK-alpha1 Antibody
AMPK-alpha1 Polyclonal Antibody for Western blot
Synonyms:
5'-AMP-activated protein kinase catalytic subunit alpha-1; 5'-AMP-activated protein kinase, catalytic alpha-1 chain; AMP -activate kinase alpha 1 subunit; AMP-activated protein kinase, catalytic, alpha-1; AMPK alpha 1; AMPK subunit alpha-1
Entrez Gene ID:
UniProt ID:
(Hu) Q13131
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Non-human primate (Nhp) Porcine (Po) |
| Immunogen: | Synthetic peptide corresponding to residues surrounding Leu519 near the carboxy terminus of human AMPK-alpha-1. |
| Ordering Information | ||||
| Pierce AMPK-alpha1 Antibody |
| Storage: | -20°C |
| Form: | 100 ul of antibody in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol. |
| Applications | Dilution * |
| Western Blot (WB) | 1:1000 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA5-17398 detects AMPK-alpha1 in human and non-human primate samples. Predicted to react with porcine based on sequence homology. PA5-17398 has been successfully used in Western blot applications. The PA5-17398 immunogen is synthetic peptide corresponding to residues surrounding Leu519 near the carboxy terminus of human AMPK-alpha-1. PA5-17398 detects AMPK-alpha1 which has a predicted molecular weight of approximately 62 kDa. |
| General Information |
| The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
| Product Images |
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AMPK-alpha1 Antibody (PA5-17398) in WB
Western Blot with anti-AMPK-alpha1 Polyclonal Antibody (PA5-17398)
Western blot analysis of AMPK-alpha1 in extracts from HeLa and HT29 cells using AMPK-alpha1 polyclonal antibody (Product # PA5-17398).
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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AMPK-alpha1 Antibodies > AMPK-alpha1 Polyclonal Antibody PA5-17398
