ABCC2 Antibody (M2II-12)
ABCC2 Monoclonal Antibody for ICC, IHC (F)
| Details | |
| Host / Isotype: | Mouse / IgG2a |
| Class: | Monoclonal |
| Type: | Antibody |
| Clone: | M2II-12 |
| Species Reactivity: | Human (Hu) |
| Immunogen: | ABCC2. |
| Ordering Information | ||||
| Pierce ABCC2 Antibody (M2II-12) |
| Storage: | -20° C, Avoid Freeze/Thaw Cycles |
| Form: | 1 ml serum-free tissue culture supernatant (250 µg immunoglobµlin/ml) in 0.7% BSA and 0.1% sodium azide. |
| Applications | Dilution * |
| Immunocytochemistry (ICC) | 1:20 |
| Immunohistochemistry (Frozen) (IHC (F)) | 1:20 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| MA1-35677 detects ABCC2 in human samples. MA1-35677 has been successfully used in immunohistochemistry (frozen) and immunocytochemistry applications. The MA1-35677 immunogen is from ABCC2. |
| General Information |
| ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia. |
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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ABCC2 Antibodies > ABCC2 Monoclonal Antibody MA1-35677
