ABCC2 Antibody (M2II-12)

ABCC2 Monoclonal Antibody for Western blot, ICC, IHC (F)

>> See 5 other antibodies for ABCC2 (MRP2)
Entrez Gene ID:
UniProt ID:
Host / Isotype: Mouse / IgG2a
Class: Monoclonal
Type: Antibody
Clone: M2II-12
Tested Species Reactivity: Human (Hu)
Immunogen: ABCC2.
Ordering Information
Pierce ABCC2 Antibody (M2II-12)
Product #
1 mL
Tested Applications Dilution *
Western Blot (WB) 1:20-1:50
Immunocytochemistry (ICC) 1:20
Immunohistochemistry (Frozen) (IHC (F)) 1:20
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Form Information
Form: Liquid
Storage Buffer: tissue culture supernatant with 0.7% BSA
Preservative: 0.1% sodium azide
Storage Conditions: 4° C
Product Specific Information
General Information
ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. This protein is expressed in the canalicular (apical) part of the hepatocyte and functions in biliary transport. Substrates include anticancer drugs such as vinblastine; therefore, this protein appears to contribute to drug resistance in mammalian cells. Several different mutations in this gene have been observed in patients with Dubin-Johnson syndrome (DJS), an autosomal recessive disorder characterized by conjugated hyperbilirubinemia.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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