Part of Thermo Fisher Scientific

ABCC1 Polyclonal Antibody

ABCC1 Antibody for Western blot

Synonyms:
ABCC1; ATP-binding cassette, sub-family C (CFTR/MRP), member 1; ABC29; ABCC; DKFZp686N04233; DKFZp781G125; GS-X; MRP; MRP1; ATP-binding cassette, sub-family C, member 1; LTC4 transporter; leukotriene C(4) transporter; multidrug resistance protein; multiple drug resistance protein 1; multiple drug resistance-associated protein
Entrez Gene ID:
(Human) 4363
UniProt ID:
P33527
Details
Host / Isotype: Goat
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu)
Immunogen: Synthetic peptide sequence (HQSDLKVDENQKAYY) corresponding to the internal amino acids of ABCC1
Ordering Information
Pierce ABCC1 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-18973 100 ug $299.00
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Storage: Store at -20°C. Minimize freezing and thawing.
Form: 100 ug of purified antibody from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. Buffered in 0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin.


Applications Dilution *
Western Blot (WB) 0.05-0.2 ug/ml
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA5-18973 targets ABCC1 in WB applications and shows reactivity with Human samples.

The PA5-18973 immunogen is synthetic peptide sequence (HQSDLKVDENQKAYY) corresponding to the internal amino acids of ABCC1.
General Information
The protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies . This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternative splicing by exon deletion results in several splice variants but maintains the original open reading frame in all forms.
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  • WB using PA5-18973
    Western Blot with anti-ABCC1 Polyclonal Antibody (PA5-18973)

    Western Blot with anti-ABCC1 Polyclonal Antibody (PA5-18973)

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    Western Blot staining of A549 cell lysate using PA5-18973 at a concentration of 0.05 ug/ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
     
 
 
(This product is for In Vitro experimental use only. Not for resale without express authorization.)