Part of Thermo Fisher Scientific

ABCB8 Polyclonal Antibody

ABCB8 Antibody for Western blot

Synonyms:
Mitochondrial ATP-binding cassette 1; M-ABC1; ATP-binding cassette sub-family B member 8, mitochondrial ; ABCB8; MABC1
Entrez Gene ID:
(Human) 11194
UniProt ID:
Q9NUT2
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu )
Immunogen: Synthetic peptide from the N-terminal region of ABCB8 conjugated to KLH.
Ordering Information
Pierce ABCB8 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-13120 100 µg $299.00
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Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Form: 100 µg (0.25 mg/ml) in PBS with 0.09% (W/V) sodium azide.


Applications Dilution *
Western Blot (WB) 1:50-1:100
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA5-13120 targets ABCB8 in WB applications and shows reactivity with Human samples. The PA5-13120 immunogen is a synthetic peptide from the N-terminal region of ABCB8 conjugated to KLH. PA5-13120 detects ABCB8 which has a predicted molecular weight of approximately 80 kDa.
General Information
The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies. This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, it may involve the compartmentalization and transport of heme, as well as peptides, from the mitochondria to the nucleus and cytosol. This protein may also play a role in the transport of phospholipids into mitochondrial membranes.
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References:
Saito S., Iida A., Sekine A.J. Hum. Genet. 47:38-50(2002)
(This product is for In Vitro experimental use only. Not for resale without express authorization.)