Part of Thermo Fisher Scientific

ABCA1 Monoclonal Antibody (5A1-1422.11)

ABCA1 Antibody for FACS

Synonyms:
ABC 1 antibody, ABC Transporter 1 antibody, ABC1 antibody, ATP-binding Cassette 1 antibody, ATP-binding Cassette Transporter 1 antibody, CERP antibody
Entrez Gene ID:
(Murine) 19, (Murine) 11303
UniProt ID:
O95477
Details
Host / Isotype: Rat / IgG2a, kappa
Class: Monoclonal
Type: Antibody
Clone: 5A1-1422.11
Species Reactivity: Murine (Ms)
Immunogen: Mouse ABCA1-expressing HeLa stable transfectants.
Ordering Information
Pierce ABCA1 Monoclonal Antibody (5A1-1422.11)
Product Number Pkg. Size Price Purchase
MA1-16937 100 µl $354.00
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Storage: -20º C, Avoid Freeze/Thaw Cycles
Form: 100 µl of whole antisera (32.4 mg/ml) containing 0.1% sodium azide.


Applications Dilution *
Flow Cytometry (FACS) 1:1000 - 1:30,000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA1-16937 detects ABCA1 protein in mouse samples.

MA1-16937 has been successfully used in flow cytometry procedures. This antibody is not reactive in Western blot or ELISA applications.

MA1-16937 immunogen is mouse ABCA1-expressing HeLa stable transfectants.

Figure 1 shows a FACS analysis of Raw (red) and Raw-cAMP (blue) cells using MA1-16937.
General Information
Mutations in the ABCA1 gene (ATP-binding cassette transporter 1) have been reported in Tangier disease (TD). TD is an autosomal recessive disorder characterized by an absence of plasma HDL, cholesterol ester depositing in the reticulo-endothelial system and deviations in cellular lipid trafficking. ABCA1 mediates the apo-A1 associated export of cholesterol and phospholipids from the cell. It is expressed on the plasma membrane and the Golgi complex, and is regulated by cholesterol flux. Regulation of the cholesterol flux between HDL and macrophages is competitive between ABCA1 and SR-BI.
Product Images
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  • FACS using MA1-16937
    Flow Cytometry with anti-ABCA1 Monoclonal Antibody [5A1-1422.11] (MA1-16937)

    Flow Cytometry with anti-ABCA1 Monoclonal Antibody [5A1-1422.11] (MA1-16937)

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  • FACS using MA1-16937
    Flow Cytometry with anti-ABCA1 Monoclonal Antibody [5A1-1422.11] (MA1-16937)

    Flow Cytometry with anti-ABCA1 Monoclonal Antibody [5A1-1422.11] (MA1-16937)

    View Product Details >>
    Raw (red) and Raw-cAMP (blue) cells using NB 400-165 at a dilution of 1:4,000
     
 
 
(This product is for In Vitro experimental use only. Not for resale without express authorization.)