Part of Thermo Fisher Scientific

ABAD Polyclonal Antibody

ABAD Antibody for Western blot, IHC

Synonyms:
hydroxyacyl-Coenzyme A dehydrogenase, type II isoform 1; 3-hydroxyacyl-CoA dehydrogenase type II; Type II HADH; 3-hydroxy-2-methylbutyryl-CoA dehydrogenase; Endoplasmic reticulum-associated amyloid beta-peptide binding protein; Short-chain type dehydrogenase/reductase XH98G2 ; ERAB, HSD17B10, SCHAD; HADH2 protein
Entrez Gene ID:
(Human) 3028
UniProt ID:
Q6IBS9
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu )
Immunogen: Synthetic peptide from the C-terminal region of ABAD conjugated to KLH.
Ordering Information
Pierce ABAD Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-13330 100 µg $299.00
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Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Form: 100 µg (0.25 mg/ml) in PBS with 0.09% (W/V) sodium azide.


Applications Dilution *
Immunohistochemistry (IHC) 1:50-1:100
Western Blot (WB) 1:100-1:500
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA5-13330 targets ABAD in WB and IHC applications and shows reactivity with Human samples. The PA5-13330 immunogen is a synthetic peptide from the C-terminal region of ABAD conjugated to KLH. PA5-13330 detects ABAD which has a predicted molecular weight of approximately 27 kDa.
General Information
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids, alcohols, and steroids. The protein has been implicated in the development of Alzheimer's disease, and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
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References:
FASEB J. 19 (6), 597-598 (2005)
FEBS Lett. 451 (3), 238-242 (1999)
J. Biol. Chem. 274 (21), 15014-15019 (1999)
J. Mol. Biol. 342 (3), 943-952 (2004)
Science 304 (5669), 448-452 (2004)
(This product is for In Vitro experimental use only. Not for resale without express authorization.)