Part of Thermo Fisher Scientific

AASS Polyclonal Antibody

AASS Antibody for Western blot, IHC

Synonyms:
Alpha-aminoadipic semialdehyde synthase, mitochondrial; LKR/SDH; Lysine ketoglutarate reductase; LKR; LOR; Saccharopine dehydrogenase; SDH; AASS
Entrez Gene ID:
(Human) 10157
UniProt ID:
Q9UDR5
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu )
Immunogen: Synthetic peptide from the center region of AASS conjugated to KLH.
Ordering Information
Pierce AASS Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-12372 100 µg $299.00
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Storage: Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
Form: 100 µg (0.25 mg/ml) in PBS with 0.09% (W/V) sodium azide.


Applications Dilution *
Immunohistochemistry (IHC) 1:10-1:50
Western Blot (WB) 1:50-1:100
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA5-12372 targets AASS in WB and IHC applications and shows reactivity with Human samples. The PA5-12372 immunogen is a synthetic peptide from the center region of AASS conjugated to KLH. PA5-12372 detects AASS which has a predicted molecular weight of approximately 102 kDa.
General Information
This gene encodes a bifunctional enzyme that catalyzes the first two steps in the mammalian lysine degradation pathway. The N-terminal and the C-terminal portions of this enzyme contain lysine-ketoglutarate reductase and saccharopine dehydrogenase activity, respectively, resulting in the conversion of lysine to alpha-aminoadipic semialdehyde. Mutations in this gene are associated with familial hyperlysinemia.
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References:
Sacksteder,K.A., Am. J. Hum. Genet. 66 (6), 1736-1743 (2000)
(This product is for In Vitro experimental use only. Not for resale without express authorization.)