Part of Thermo Fisher Scientific

AANAT Polyclonal Antibody

AANAT Antibody for Western blot

Synonyms:
SNAT
Entrez Gene ID:
(Human) 15
UniProt ID:
Q16613
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Non-human primate (Nhp)
Immunogen: Human AANAT
Ordering Information
Pierce AANAT Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA1-32265 100 µl $379.00
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Storage: Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
Form: 100 µl of antibody in 0.1N glacial acetic acid containing 0.1% BSA and neutralized using 10X PBS containing NaOH to a final pH of 6.8.. For extended storage add 50% glycerol, aliquot and store at -20ºC or below.


Applications Dilution *
Western Blot (WB) Assay dependent
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA1-32265 detects AANAT from human, non-human primate samples.

PA1-32265 has been successfully used in Western blot applications.

The PA1-32265 immunogen is: Human AANAT
General Information
The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)