AANAT Antibody
AANAT Polyclonal Antibody for Western blot
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) Non-human primate (Nhp) |
| Immunogen: | Human AANAT |
| Ordering Information | ||||
| Pierce AANAT Antibody |
| Storage: | Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. |
| Form: | 100 ul of immunoaffinity purified antibody from serum in 0.1N glacial acetic acid containing 0.1% BSA and neutralized using 10X PBS with NaOH, pH 6.8. |
| Applications | Dilution * |
| Immunocytochemistry (ICC) | 1:200 |
| Immunofluorescence (IF) | 1:200 |
| Western Blot (WB) | Assay dependent |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA1-32265 detects AANAT from human, non-human primate samples. PA1-32265 has been successfully used in Western blot applications. The PA1-32265 immunogen is: Human AANAT |
| General Information |
| The protein encoded by this gene belongs to the acetyltransferase superfamily. It is the penultimate enzyme in melatonin synthesis and controls the night/day rhythm in melatonin production in the vertebrate pineal gland. Melatonin is essential for the function of the circadian clock that influences activity and sleep. This enzyme is regulated by cAMP-dependent phosphorylation that promotes its interaction with 14-3-3 proteins and thus protects the enzyme against proteasomal degradation. This gene may contribute to numerous genetic diseases such as delayed sleep phase syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. |
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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AANAT Antibodies > AANAT Polyclonal Antibody PA1-32265
