Part of Thermo Fisher Scientific

A20/TNFAIP3 Polyclonal Antibody

A20/TNFAIP3 Antibody for IP, Western blot

Synonyms:
OTU domain-containing protein 7C; TNF alpha-induced protein 3; putative DNA-binding protein A20; tumor necrosis factor alpha-induced protein 3; tumor necrosis factor inducible protein A20; zinc finger protein A20
Entrez Gene ID:
(Human) 7128
UniProt ID:
P21580
Details
Host / Isotype: Rabbit
Class: Polyclonal
Type: Antibody
Species Reactivity: Human (Hu) Non-human primate (Nhp)
Immunogen: Synthetic peptide corresponding to residues surrounding Gly267 of human A20/TNFAIP3.
Ordering Information
Pierce A20/TNFAIP3 Polyclonal Antibody
Product Number Pkg. Size Price Purchase
PA5-17149 100 ul $230.00
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Storage: -20°C
Form: 100 ul of antibody in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 ug/ml BSA and 50% glycerol.


Applications Dilution *
Immunoprecipitation (IP) 1:25
Western Blot (WB) 1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
PA5-17149 targets A20/TNFAIP3 in IP, and WB applications and shows reactivity with Human, and Non-human primate samples.

The PA5-17149 immunogen is synthetic peptide corresponding to residues surrounding Gly267 of human A20/TNFAIP3.

PA5-17149 detects A20/TNFAIP3 which has a predicted molecular weight of approximately 82 kDa.
General Information
This gene was identified as a gene whose expression is rapidly induced by the tumor necrosis factor (TNF). The protein encoded by this gene is a zinc finger protein, and has been shown to inhibit NF-kappa B activation as well as TNF-mediated apoptosis. Knockout studies of a similar gene in mice suggested that this gene is critical for limiting inflammation by terminating TNF-induced NF-kappa B responses.
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)