CD117 Antibody
CD117 Polyclonal Antibody for IHC (P)
Synonyms:
mast/stem cell growth factor receptor, proto-oncogene c-Kit, proto-oncogene tyrosine-protein kinase Kit, soluble KIT variant 1, tyrosine-protein kinase Kit
Entrez Gene ID:
UniProt ID:
(Hu) P10721
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | A synthetic peptide from C-terminus of human CD117/c-kit protein |
| Ordering Information | ||||
| Pierce CD117 Antibody |
| Storage: | 4° C, do not freeze |
| Form: | 500 ul of total IgG purified from rabbit anti-serum by Protein A chromatography (4 mg/ml). Prepared in 10mM PBS, pH 7.4, with 0.2% BSA and 0.09% sodium azide. |
| Applications | Dilution * |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:50 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA5-16458 targets CD117 in IHC (P) applications and shows reactivity with Human samples. The PA5-16458 immunogen is a synthetic peptide from C-terminus of human CD117/c-kit protein. |
| General Information |
| c-kit is a transmembrane receptor tyrosine kinase. It binds to stem cell factor (SCF). It is expressed in many tissues and cells. C-kit/SCf is involved in development of several lineages of stem cells, such as germ cells, neural crest-derived melanocytes and hematopoietic precursor cells Antibody to CD117/c-kit may be helpful in the histopathological identification of gastrointestinal stromal tumors (GIST). |
| Product Images |
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CD117 Antibody (PA5-16458) in IHC
Immunohistochemistry with anti-CD117 Polyclonal Antibody (PA5-16458)
Formalin-fixed, paraffin-embedded human stroma tumor stained with CD117/c-Kit antibody using peroxidase-conjugate and AEC chromogen. Note staining of tumor cells. -
CD117 Antibody (PA5-16458) in IHC
Immunohistochemistry with anti-CD117 Polyclonal Antibody (PA5-16458)
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CD117 Antibody (PA5-16458) in IHC
Immunohistochemistry with anti-CD117 Polyclonal Antibody (PA5-16458)
Formalin-fixed, paraffin-embedded human tonsil stained with CD117 / c-Kit antibody using peroxidase-conjugate and AEC chromogen. Note staining of mast cells.
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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CD117 Antibodies > CD117 Polyclonal Antibody PA5-16458
