GHRF Receptor Antibody
GHRF Receptor Polyclonal Antibody for ICC, IHC (P), Western blot
Synonyms:
Growth Hormone Releasing Hormone Receptor
Entrez Gene ID:
UniProt ID:
(Hu) Q02643
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic peptide, KLH conjugated, corresponding to residues R(403) T R A K W T T P S R S A A K V L T S M(422) of human GHRH-R. |
| Ordering Information | ||||
| Pierce GHRF Receptor Antibody |
| Storage: | -20° C, Avoid Freeze/Thaw Cycles |
| Form: | 100 ul of antiserum containing 0.05% sodium azide. |
| Applications | Dilution * |
| Immunocytochemistry (ICC) | 1:3,000 |
| Western Blot (WB) | 1:3,000 |
| Immunohistochemistry (Paraffin) (IHC (P)) | 1:1,000 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA3-117 detects GHRH-R in human samples. PA3-117 has been successfully used in Western blot, immunocytochemistry and immunohistochemistry procedures. By Western blot, this antibody detects an ~40 kDa protein representing GHRH-R in human samples. In immunohistochemistry, GHRH-R immunoreactivity is predominantly localized at the plasma membrane. The PA3-117 immunizing peptide corresponds to amino acid residues 403-422 from human GHRH-R. |
| General Information |
| Growth Hormone Releasing Hormone (GHRH) is a member of a family of peptide hormones that also includes VIP (vasoactive intestinal polypeptide) and PACAP (pituitary adenylate cyclase-activating polypeptide). It is a hypothalamic peptide that binds to G-protein coupled receptors to stimulate secretion and synthesis of growth hormone (GH). GHRH receptor proteins have been identified on the plasma membrane of primary human tumor cells, and are thought to be involved in the growth of a variety of cancer cells. |
| Product Images |
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GHRF Receptor Antibody (PA3-117) in IHC
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Immunohistochemistry with anti-GHRF Receptor Polyclonal Antibody (PA3-117)
Immunohistochemical staining of GHRH-R in human ovarian carcinoma samples using PA3-117.
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| PubMed References: |
| Immunocytochemistry | ||
| Species / Dilution | Summary | |
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Hu / 1 ug/ml |
PA3-117 was used in immunocytochemistry, immunohistochemistry and western blot to study the GHRH receptor immunocytochemical localization by a novel antibody in human tumours
Eur J Cancer. 2006 Sep;42(14):2390-6.
"Immunocytochemical localisation of plasma membrane GHRH receptors in human tumours using a novel anti-peptide antibody." Author(s): Schulz S, Röcken C, Schulz S Number of Citations: 1 (See PubMed article  )
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| Immunohistochemistry | ||
| Species / Dilution | Summary | |
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Hu / 2 ug/ml |
PA3-117 was used in immunocytochemistry, immunohistochemistry and western blot to study the GHRH receptor immunocytochemical localization by a novel antibody in human tumours
Eur J Cancer. 2006 Sep;42(14):2390-6.
"Immunocytochemical localisation of plasma membrane GHRH receptors in human tumours using a novel anti-peptide antibody." Author(s): Schulz S, Röcken C, Schulz S Number of Citations: 1 (See PubMed article )
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| Western Blot | ||
| Species / Dilution | Summary | |
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Hu / 1 ug/ml |
PA3-117 was used in immunocytochemistry, immunohistochemistry and western blot to study the GHRH receptor immunocytochemical localization by a novel antibody in human tumours
Eur J Cancer. 2006 Sep;42(14):2390-6.
"Immunocytochemical localisation of plasma membrane GHRH receptors in human tumours using a novel anti-peptide antibody." Author(s): Schulz S, Röcken C, Schulz S Number of Citations: 1 (See PubMed article )
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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GHRF Receptor Antibodies > GHRF Receptor Polyclonal Antibody PA3-117
