Endostatin Antibody
Endostatin Polyclonal Antibody for Western blot
Synonyms:
Alpha 1 Collagen type 18 (XVIII)(COL18A1), COL18A1, Endostatin, KNO
Entrez Gene ID:
UniProt ID:
(Hu) P39060
| Details | |
| Host / Isotype: | Rabbit |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Human (Hu) |
| Immunogen: | Synthetic Peptide: R(129) R L M/T E S Y C E T W R T E(142) |
| Ordering Information | ||||
| Pierce Endostatin Antibody |
| Storage: | -20° C, Avoid Freeze/Thaw Cycles |
| Form: | 100 µg of epitope affinity purified IgG (1 mg/ml) in PBS containing 1 mg/ml BSA and 0.05% sodium azide. |
| Applications | Dilution * |
| Western Blot (WB) | 2 µg/ml |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| PA1-601 detects recombinant human endostatin. PA1-601 has been successfully used in Western blot procedures. By Western blot, this antibody detects a 20 kDa protein representing recombinant human endostatin. PA1-601 immunizing peptides are two peptides derived from mouse and human endostatin protein corresponding to amino acid residues 129-142 of endostatin. |
| General Information |
| Endostatin is a 20-kDa proteolytic COOH-terminal fragment derived from collagen XVIII. Endostatin reduces endothelial cell proliferation and acts as a potent inhibitor of angiogenesis and tumor growth. |
| PubMed References: |
| Immunohistochemistry | ||
| Species / Dilution | Summary | |
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Ms / Not Cited |
PA1-601 was used in immunohistochemistry and western blot to study the effect of antiangiogenic gene therapy on tumor metastases
Cancer Gene Ther. 2005 Jan;12(1):35-45.
"Intramuscular delivery of antiangiogenic genes suppresses secondary metastases after removal of primary tumors." Author(s): Sun X, Qiao H, Jiang H, Zhi X, Liu F, Wang J, Liu M, Dong D, Kanwar JR, Xu R, Krissansen GW Number of Citations: 1 (See PubMed article  )
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Ms / Not Cited |
PA1-601 was used in immunohistochemistry and western blot to investigate the effect of endostatin gene therapy on the efficacy of paclitaxel against breast cancer
J Biomed Sci. 2008 Jan;15(1):99-109.
"Endostatin gene therapy enhances the efficacy of paclitaxel to suppress breast cancers and metastases in mice." Author(s): Li J, Dong X, Xu Z, Jiang X, Jiang H, Krissansen GW, Sun X Number of Citations: 1 (See PubMed article )
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| Western Blot | ||
| Species / Dilution | Summary | |
|
Ms / Not Cited |
PA1-601 was used in immunohistochemistry and western blot to study the effect of antiangiogenic gene therapy on tumor metastases
Cancer Gene Ther. 2005 Jan;12(1):35-45.
"Intramuscular delivery of antiangiogenic genes suppresses secondary metastases after removal of primary tumors." Author(s): Sun X, Qiao H, Jiang H, Zhi X, Liu F, Wang J, Liu M, Dong D, Kanwar JR, Xu R, Krissansen GW Number of Citations: 1 (See PubMed article )
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Ms / Not Cited |
PA1-601 was used in immunohistochemistry and western blot to investigate the effect of endostatin gene therapy on the efficacy of paclitaxel against breast cancer
J Biomed Sci. 2008 Jan;15(1):99-109.
"Endostatin gene therapy enhances the efficacy of paclitaxel to suppress breast cancers and metastases in mice." Author(s): Li J, Dong X, Xu Z, Jiang X, Jiang H, Krissansen GW, Sun X Number of Citations: 1 (See PubMed article )
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Nhp / 0 |
PA1-601 was used in western blot to investigate the effect of gene transfer of endostatin on the therapeutic efficacy of doxorubicin against human hepatocellular carcinomas
Cancer Sci. 2007 Sep;98(9):1381-7.
"Gene transfer of endostatin enhances the efficacy of doxorubicin to suppress human hepatocellular carcinomas in mice." Author(s): Liu F, Tan G, Li J, Dong X, Krissansen GW, Sun X Number of Citations: 1 (See PubMed article )
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(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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Endostatin Antibodies > Endostatin Polyclonal Antibody PA1-601
