Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles.
100 ul of ascitic fluid containing 0.03% sodium azide.
Western Blot (WB)
1/500 - 1/2000
1/200 - 1/1000
1/200 - 1/1000
Flow Cytometry (FACS)
1/200 - 1/400
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
Product Specific Information
MA5-15906 targets FGG in FACS, IF, IHC, and WB applications and shows reactivity with Human samples.
The MA5-15906 immunogen is purified recombinant fragment of human FGG expressed in E. Coli. .
MA5-15906 detects FGG which has a predicted molecular weight of approximately 52kDa.
The protein encoded by this gene is the gamma component of fibrinogen, a blood-borne glycoprotein comprised of three pairs of nonidentical polypeptide chains. Following vascular injury, fibrinogen is cleaved by thrombin to form fibrin which is the most abundant component of blood clots. In addition, various cleavage products of fibrinogen and fibrin regulate cell adhesion and spreading, display vasoconstrictor and chemotactic activities, and are mitogens for several cell types. Mutations in this gene lead to several disorders, including dysfibrinogenemia, hypofibrinogenemia and thrombophilia. Alternative splicing results in two transcript variants encoding different isoforms.
FGG Antibody (MA5-15906) in IHC
Immunohistochemistry with anti-FGG Monoclonal Antibody [4H9] (MA5-15906)