PDGF Receptor beta Antibody (G.290.3)

PDGF Receptor beta Monoclonal Antibody for ICC, IHC (F), IHC (P), IP, Western blot

>> See 28 other antibodies for PDGFRB (CD140 antigen-like family member B; PDGF-R-beta; beta-type platelet-derived growth factor receptor)

Synonyms:

CD140 antigen-like family member B; PDGF-R-beta; beta-type platelet-derived growth factor receptor

Entrez Gene ID:

(Hu) 5159, (Ms) 18596, (Rt) 24629

UniProt ID:

(Hu) P09619, (Ms) P05622, (Rt) Q05030

Details

Host / Isotype:	Rabbit / IgG
Class:	Monoclonal
Type:	Antibody
Clone:	G.290.3
Species Reactivity:	Human (Hu) Mouse (Ms) Rat (Rt)
Immunogen:	GST fusion protein containing a carboxy-terminal fragment of human PDGF receptor-beta.

Ordering Information
Pierce PDGF Receptor beta Antibody (G.290.3)

Product #

MA5-15143

Size

100 ul

Price

$242.00

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Storage:	-20°C
Form:	100 ul of antibody in 10 mM sodium HEPES (pH 7.5), 150 mM NaCl, 100 ug/ml BSA, 50% glycerol and less than 0.02% sodium azide.

Applications	Dilution *

Immunohistochemistry (Frozen) (IHC (F))	1:100
Immunohistochemistry (Paraffin) (IHC (P))	1:100
Immunocytochemistry (ICC)	1:100
Immunoprecipitation (IP)	1:50
Western Blot (WB)	1:1000
* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.

Product Specific Information

MA5-15143 targets PDGF Receptor beta in ICC, IHC (F), IHC (P), IP, and WB applications and shows reactivity with Human, Murine, and Rat samples.

The MA5-15143 immunogen is gST fusion protein containing a carboxy-terminal fragment of human PDGF receptor-beta.

MA5-15143 detects PDGF Receptor beta which has a predicted molecular weight of approximately 190 kDa.

General Information

This gene encodes a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. This gene is flanked on chromosome 5 by the genes for granulocyte-macrophage colony-stimulating factor and macrophage-colony stimulating factor receptor; all three genes may be implicated in the 5-q syndrome. A translocation between chromosomes 5 and 12, that fuses this gene to that of the translocation, ETV6, leukemia gene, results in chronic myeloproliferative disorder with eosinophilia.

Product Images

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PDGF Receptor beta Antibody (MA5-15143) in IF

Immunofluorescence with anti-PDGF Receptor beta Monoclonal Antibody [G.290.3] (MA5-15143)

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Immunofluorescent analysis of PDGF Receptor beta in NIH/3T3 cells, PDGF-treated, using a PDGF Receptor beta monoclonal antibody (Product # MA5-15143) (green). DNA is labeled using a fluorescent blue dye.

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PDGF Receptor beta Antibody (MA5-15143) in IF

Immunofluorescence with anti-PDGF Receptor beta Monoclonal Antibody [G.290.3] (MA5-15143)

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PDGF Receptor beta Antibody (MA5-15143) in IHC

Immunohistochemistry with anti-PDGF Receptor beta Monoclonal Antibody [G.290.3] (MA5-15143)

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Immunohistochemical analysis of PDGF Receptor beta in paraffin-embedded human colon carcinoma using a PDGF Receptor beta monoclonal antibody (Product # MA5-15143).

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PDGF Receptor beta Antibody (MA5-15143) in WB

Western Blot with anti-PDGF Receptor beta Monoclonal Antibody [G.290.3] (MA5-15143)

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Western blot analysis of PDGF Receptor beta in extracts from NIH/3T3 and C6 cell lines using PDGF Receptor beta monoclonal antibody (Product # MA5-15143).

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(This product is for In Vitro experimental use only. Not for resale without express authorization.)