MAPK8 Antibody
(This product has been discontinued.)
Please click the link below to find suitable replacements for this discontinued product.>> See 16 other antibodies for MAPK8
MAPK8 Polyclonal Antibody for Western blot
Synonyms:
JNK, PRKM8, SAPK1
Entrez Gene ID:
UniProt ID:
(Hu) P45983, (Ms) Q91Y86
| Details | |
| Host / Isotype: | Rabbit / IgG |
| Class: | Polyclonal |
| Type: | Antibody |
| Species Reactivity: | Xenopus laevis (Xl) Human (Hu) Mouse (Ms) Rat (Rt) |
| Immunogen: | Mitogen-activated protein kinase 8 |
| Ordering Information | ||||
| Pierce MAPK8 Antibody |
Product #
82381
Size
525 ul
Price
$264.00
Purchase
(DISCONTINUED)
| Storage: | -20°C |
| Applications | Dilution * |
| Western Blot (WB) | 1:200 |
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* Suggested working dilutions are given as a guide only. It is recommended that the user titrates the product for use in their own experiment using appropriate negative and positive controls.
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| Product Specific Information |
| 82381 targets MAPK8 in WB applications and shows reactivity with Human, Murine, Rat, and Xenopus laevis samples. The 82381 immunogen is mitogen-activated protein kinase 8. 82381 detects MAPK8 which has a predicted molecular weight of approximately 46 kDa. |
| General Information |
| The protein encoded by this gene is a member of the MAP kinase family. MAP kinases act as an integration point for multiple biochemical signals, and are involved in a wide variety of cellular processes such as proliferation, differentiation, transcription regulation and development. This kinase is activated by various cell stimuli, and targets specific transcription factors, and thus mediates immediate-early gene expression in response to cell stimuli. The activation of this kinase by tumor-necrosis factor alpha (TNF-alpha) is found to be required for TNF-alpha induced apoptosis. This kinase is also involved in UV radiation induced apoptosis, which is thought to be related to cytochrom c-mediated cell death pathway. Studies of the mouse counterpart of this gene suggested that this kinase play a key role in T cell proliferation, apoptosis and differentiation. Four alternatively spliced transcript variants encoding distinct isoforms have been reported. |
| Product Images |
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MAPK8 Antibody (82381) in WB
Western Blot with anti-MAPK8 Polyclonal Antibody (82381)
A549 cells were lysed 72 hours after transfection. Cells were transfected with Transfection Reagent alone (Lane 1), 100nM ON-TARGETplus siCONTROL Non-Targeting Pool (Lane 2), or 100nM ON-TARGETplus MAPK8 siRNA (Lane 3). Western blot data for Cyclophilin B is included as a control for equal protein loading.
| References: |
| http://www.ncbi.nlm.nih.gov (Sept. 2007) |
(This product is for In Vitro experimental use only. Not for resale without express authorization.)
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MAPK8 Antibodies > MAPK8 Polyclonal Antibody 82381
